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Ocular Cancer Treatment
Eye Plaque Brachytherapy is a Safe and Effective Means of Eye Preservation in Cases of Ocular Melanoma1
Eye Plaque Treatment Using Cesium-131 Provides the Following Advantages:
- Cesium-131 provides better dose homogeneity than either Iodine-125 or Palladium-103.2,3
- Cesium-131 allows for greater penetration of therapeutic dose while maintaining lower scleral dose compared with I-125 or Pd-103.2,3
- The shorter half-life of Cs-131 (than I-125 or Pd-103) minimizes concerns for in-house decay and radioactivity storage.
- Cesium-131 may be more beneficial for certain lesions than either Pd-103 or I-125.2,3
IsoRay's Cesium-131 loose seeds may be used to create a custom-made radioactive ophthalmic plaque by affixing Cesium-131 seeds into a seed carrier and gold or steel plaque.
1. COMS Group. Twelve year mortality rates and prognostic factors: COMS report no. 28. Arch Opthamol (Chicago). 124:1684-93, 2006.
2. Rivard MJ, Melhus CS, Shioshansi S, Morr J. The impact of prescription depth, dose rate, plaque size, and source loading on the central axis using 103Pd, 125I, and 131Cs. Brachytherapy 7:327-35, 2008.
3. Melhus CS, Rivard MJ. COMS eye plaque brachytherapy dosimetry simulations for 103Pd, 125I, and 131Cs. Med Phys 35:3364-71, 2008.